An Energy Efficient, Load Balancing, and Reliable Routing Protocol for Wireless Sensor Networks

AN ENERGY EFFICIENT, LOAD BALANCING, AND RELIABLE ROUTING PROTOCOL FOR WIRELESS SENSOR NETWORKS by Kamil Samara The University of Wisconsin-Milwaukee, 2016 Under the Supervision of Professor Hossein Hosseini The Internet of Things (IoT) is shaping the future of Computer Networks and Computing in general, and it is gaining ground very rapidly. The whole idea has originated from the pervasive presence of a variety of things or objects equipped with the internet connectivity. These devices are becoming cheap and ubiquitous, at the same time more powerful and smaller with a variety of onboard sensors. All these factors with the availability of unique addressing, provided by the IPv6, has made these devices capable of collaborating with each other to accomplish common tasks. Mobile AdHoc Networks (MANETS) and Wireless Sensor Networks (WSN) in particular play a major role in the backbone of IoT. Routing in Wireless Sensor Networks (WSN) has been a challenging task for researchers in the last several years because the conventional routing algorithms, such as the ones used in IP-based networks, are not well suited for WSNs because these conventional routing algorithms heavily rely on large routing tables that need to be updated periodically. The size of a WSN could range from hundreds to tens of thousands of nodes, which will make routing tables’ size very large. Managing large routing tables is not feasible in WSNs due to the limitations of resources. The directed diffusion algorithm is a well-known routing algorithm for Wireless Sensor Networks (WSNs). The directed diffusion algorithm saves energy by sending data packets hop by hop and by enforcing paths to avoid flooding. The directed diffusion algorithm does not attempt to find the best or healthier paths (healthier paths are paths that use less total energy than others and avoid critical nodes). Hence the directed diffusion algorithm could be improved by enforcing the use of healthier paths, which will result in less power consumption. We propose an efficient routing protocol for WSNs that gives preference to the healthier paths based on the criteria of the total energy available on the path, the path length, and the avoidance of critical nodes. This preference is achieved by collecting information about the available paths and then using non-incremental machine learning to enforce path(s) that meet our criteria. In addition to preferring healthier paths, our protocol provides Quality of Service (QoS) features through the implementation of differentiated services, where packets are classified as critical, urgent, and normal, as defined later in this work. Based on this classification, different packets are assigned different priority and resources. This process results in higher reliability for the delivery of data, and shorter delivery delay for the urgent and critical packets. This research includes the implementation of our protocol using a Castalia Simulator. Our simulation compares the performance of our protocol with that of the directed diffusion algorithm. The comparison was made on the following aspects: • Energy consumption • Reliable delivery • Load balancing • Network lifetime • Quality of service Simulation results did not point out a significant difference in performance between the proposed protocol and the directed diffusion algorithm in smaller networks. However, when the network’s size started to increase the results showed better performance by the proposed protocol

Eliminating repeated patterns to achieve better audio compression

EThOS - Electronic Theses Online ServiceGBUnited Kingdo

NephCure Accelerating Cures Institute: A Multidisciplinary Consortium to Improve Care for Nephrotic Syndrome

NephCure Accelerating Cures Institute (NACI) is a collaborative organization sponsored by NephCure Kidney International and the University of Michigan. The Institute is composed of 7 cores designed to improve treatment options and outcomes for patients with glomerular disease: Clinical Trials Network, Data Warehouse, Patient-Reported Outcomes (PRO) and Endpoints Consortium, Clinical Trials Consulting Team, Quality Initiatives, Education and Engagement, and Data Coordinating Center. Methods: The Trials Network includes 22 community- and hospital-based nephrology practices, 14 of which are trial-only sites. Eight sites participate in the NACI Registry, and as of October 2017, 1054 patients are enrolled with diagnoses including but not limited to focal segmental glomerulosclerosis, minimal change disease, membranous nephropathy, IgA nephropathy, and childhood-onset nephrotic syndrome. By using electronic health record data extraction, robust and efficient clinical data are captured while minimizing the burden to site-based network staff. Results: The Data Warehouse includes her-extracted data from registry patients, PRO development data, and data from completed observational studies and clinical trials. The Clinical Trial Consulting Team provides support for trial design in rare diseases leveraging these data. The PRO and Endpoints Consortium develops shorter-term endpoints while capturing the patient-reported significance of interventions under study. The Quality Initiatives and Education/Engagement cores elevate the level of care for patients. The Data Coordinating Center manages the analysis and operations of the Institute. Conclusion: By engaging with patients, academia, industry, and patient advocate community representatives, including our Patient Advisory Board, NACI strives for better outcomes and treatments using evidence-based support for clinical trial design

Evaluation of a quality improvement intervention to reduce anastomotic leak following right colectomy (EAGLE): pragmatic, batched stepped-wedge, cluster-randomized trial in 64 countries

Background Anastomotic leak affects 8 per cent of patients after right colectomy with a 10-fold increased risk of postoperative death. The EAGLE study aimed to develop and test whether an international, standardized quality improvement intervention could reduce anastomotic leaks. Methods The internationally intended protocol, iteratively co-developed by a multistage Delphi process, comprised an online educational module introducing risk stratification, an intraoperative checklist, and harmonized surgical techniques. Clusters (hospital teams) were randomized to one of three arms with varied sequences of intervention/data collection by a derived stepped-wedge batch design (at least 18 hospital teams per batch). Patients were blinded to the study allocation. Low- and middle-income country enrolment was encouraged. The primary outcome (assessed by intention to treat) was anastomotic leak rate, and subgroup analyses by module completion (at least 80 per cent of surgeons, high engagement; less than 50 per cent, low engagement) were preplanned. Results A total 355 hospital teams registered, with 332 from 64 countries (39.2 per cent low and middle income) included in the final analysis. The online modules were completed by half of the surgeons (2143 of 4411). The primary analysis included 3039 of the 3268 patients recruited (206 patients had no anastomosis and 23 were lost to follow-up), with anastomotic leaks arising before and after the intervention in 10.1 and 9.6 per cent respectively (adjusted OR 0.87, 95 per cent c.i. 0.59 to 1.30; P = 0.498). The proportion of surgeons completing the educational modules was an influence: the leak rate decreased from 12.2 per cent (61 of 500) before intervention to 5.1 per cent (24 of 473) after intervention in high-engagement centres (adjusted OR 0.36, 0.20 to 0.64; P < 0.001), but this was not observed in low-engagement hospitals (8.3 per cent (59 of 714) and 13.8 per cent (61 of 443) respectively; adjusted OR 2.09, 1.31 to 3.31). Conclusion Completion of globally available digital training by engaged teams can alter anastomotic leak rates. Registration number: NCT04270721 (http://www.clinicaltrials.gov)